The Zen Sleek is a Zen Touch descendant with 20 GB hard disk storage, FM radio and microphone for live recordings. It is smaller than the Zen Touch, and boasts an aluminum casing. It can synchronize with Outlook to hold the calendar, address book, and tasks list. It also has a USB mass storage mode, which can be used to partition part of the disk for data files only. It supports MP3, WAV and WMA playback, and gives up to 20 hours of battery life (depending on usage).

It uses the same style 'touchpad' as the Zen Touch; but the 'OK' button has been removed. Instead, the user taps the touchpad to make a selection, in the same manner as a laptop touchpad.